COPD Outcomes-based Network for Clinical Effectiveness and Research Translation - Comparative Effectiveness Research (CONCERT-CER)
The CONCERT-CER program has developed a state-of-the-art research infrastructure that will accelerate the development and conduct of multi-center studies that are responsive to stakeholder priorities for comparative effectiveness research (CER) in patients with chronic obstructive pulmonary disease (COPD). By moving the focus beyond efficacy to promoting care that is effective in a diverse set of health care settings, CONCERT-CER is uniquely suited to become the premier US-based CER consortium for conducting groundbreaking, high-impact research to support healthcare decisions for patients with COPD. The Specific Aims of the CONCERT-CER program are:
1. To develop and support a novel national CONCERT Data Hub for CER studies in diverse patient populations in managed care and non-managed care settings. The Data Hub will link administrative and electronic sources of clinical data from 200,000 patients with and without COPD and will provide longitudinal data on care practices and health outcomes across diverse, real-world, healthcare settings. This infrastructure will greatly facilitate the design of CER studies.
2. To enrich the CONCERT Data Hub by collecting additional detailed clinical and questionnaire information on a sample (N=1200; 200 in each of 6 Clinical Centers) selected from the Data Hub. These added data (e.g., lung function, quality-of-life, evaluation of self-management skills) will leverage the usefulness of the larger Data Hub by linking it to disease severity, functional status, and various patient-centered outcomes
EHR/EMR System or Vendor
Variety of vendor supplied and home grown products, including billing systems from GE Healthcare (IDX Flowcast), Eclipsys (TSI) and clinical systems and data warehouses developed by Cerner, EPIC, Oracle and Clarity.
Primary care or ambulatory clinics, Inpatient facilities, Emergency departments, Specialty clinics, Academic medical centers, Community health centers
Electronic Health/Medical Records (EHR or EMR), Diagnostic data, Patient Registries, Patient-Reported Outcomes, Personal Health Records, Data Collected for Independent
Geographic scope type
Locations of Focus
Kaiser Permanente, Northwest Region, (KPNW). KPNW is a group-model, managed care organization providing comprehensive, prepaid care to members living in NW Oregon and SW Washington. VA Puget Sound Health Care System centered in Seattle, Washington . Non-federal health systems. The non-federal health systems component of CONCERT (University of Chicago; University of Illinois at Chicago; University of Washington; University of North Carolina at Chapel Hill; and affiliated community hospitals) represent a geographically diverse group of academic medical centers and community teaching hospitals each consisting of a large tertiary care medical center and an associated network of primary and specialty care practice sites.
Population Network Size
Approximately 200,000 patients across 6 Clinical Centers with and without COPD are included in the CONCERT DataHub.
Center for Health Research, Kaiser Permanente Northwest, AsthmaCER Hub (Brian Hazlehurst, PhD, PI), HMO Research Network (HMORN), Bioinformatics cores (personnel and resources )at selected Centers for Clinical and Translational Award (CTSA) institutions
CONCERT members have active partnerships with other consortia, including the CTSA Consortium, VA Health System, and HMO Research Network.
CER/PCOR Study Priority Populations
Low-income groups, Minority groups, Women, The elderly, Individuals with disabilities, Individuals who need chronic care, Individuals who need end-of-life care, Individuals who live in inner-city areas, Individuals who live in rural areas, Arthritis and nontraumatic joint disorders (Muscle, bone, and joint conditions), Cancer, Cardiovascular disease, including stroke and hypertension (Heart and blood vessel conditions), Dementia, including Alzheimer's Disease (Brain and nerve conditions), Depression and other mental health disorders (Mental health), Developmental delays, attention-deficit hyperactivity disorder, and autism (Developmental delays, ADHD, autism), Diabetes mellitus (Diabetes), Functional limitations and physical disabilities, Obesity, Pulmonary disease/asthma (Breathing conditions)
Pharmacotherapy for COPD, pulmonary rehabilitation, use of supplemental oxygen, smoking cessation, exercise programs, quality improvement bundles, diagnostic testing, management of patients with multiple chronic conditions.
Outcome(s) of Interest
Patient reported outcomes, lung function, acute care utilization.
Stakeholder engagement to prioritize research using Analytic Hierarchy Process (Am J Respir Crit Care Med 2012; Epub ahead of print). PMID 23155144.
Acknowledgement of Funders
This award is funded under the American Recovery and Reinvestment Act of 2009, NIH Award number: 1RC2HL101618-01