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A Case Study of Pediatric Asthma Alerts from the Beacon Community Program in Cincinnati: Technology is Just the First Step, Tara Trudnak, Mona Monsour, Keith Mandel, Hadley Sauers, Gerry Pandzik, Carl Donisi, and Gerry Fairbrother

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Accelerating Regulatory Progress in Multi-Institutional Research, Andrea Paolino, Sherry L. Lauf, Lisa E. Pieper, Melissa Goff, Jared Rowe, and Ileana M. Vargas

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Accelerating Regulatory Progress in Multi-Institutional Research, Andrea R. Paolino, Sherry L. Lauf, Lisa E. Pieper, Jared Rowe, Ileana M. Vargas, Melissa A. Goff, Matthew F. Daley, Leah Tuzzio, and John F. Steiner

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Accuracy of Charge Transparency: Processes to Validate Electronic Data from State and Federal Repositories for Hospital Charges, Bobbie Kite

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Achieving and Sustaining Automated Health Data Linkages for Learning Systems: Barriers and Solutions, Erik G. Van Eaton, Allison B. Devlin, Emily Beth Devine, David R. Flum, and Peter Tarczy-Hornoch

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Achieving Automated Health Data Linkages for Learning Healthcare Systems: Lessons Learned, Erik van Eaton MD; Allison Devlin; Beth Devine MBA, PharmD, PhD; David R. Flum MD, MPH; and Peter Tarczy-Hornoch MD

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Achieving the Promise of Electronic Health Record-enabled Quality Measurement: a Measure Developer’s Perspective, Phyllis Torda and Aldo Tinoco

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A Conceptual Framework for Big Data in Community-wide Population Healthcare Delivery and Research, Hadi Kharrazi

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Active Use of Electronic Health Records (EHRs) and Personal Health Records (PHRs) for Epidemiologic Research: Sample Representativeness and Nonresponse Bias in a Study of Women During Pregnancy, Julie K. Bower, Claire E. Bollinger, Randi E. Foraker, Darryl B. Hood, Abigail B. Shoben, and Albert M. Lai

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Adapting Practice-Based Intervention Research to Electronic Environments: Opportunities and Complexities at Two Institutions, Christopher J. Stille, Steven A. Lockhart, Julie A. Maertens, Christi A. Madden, and Paul M. Darden

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Addressing Sustainability and Informatics Challenges for Clinical Data Registries, Chris Boone

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Addressing Variations in Data Quality to Facilitate Multi-Institution Comparative Effectiveness Research, Michael G. Kahn, Jeffrey Brown, Daniella Meeker, Patrick Ryan, and Lisa M. Schilling

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A Digital Architecture for a Network-Based Learning Health System – Integrating Chronic Care Management, Quality Improvement, and Research, Keith Marsolo; Peter A. Margolis; Christopher B. Forrest MD, PhD; Richard B. Colletti; and John J. Hutton

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Advances in Patient Reported Outcomes: The NIH PROMIS Measures, Joan E. Broderick; Esi Morgan DeWitt M.D., M.S.C.E; Nan Rothrock PhD; Paul K. Crane M.D., M.P.H; and Christopher B. Forrest M.D., Ph.D.

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Advances in Patient Reported Outcomes: The NIH PROMIS Measures, Joan E. Broderick Ph.D.; Esi Morgan DeWitt M.D., M.S.C.E; Nan Rothrock PhD; Paul K. Crane M.D., M.P.H; and Christopher B. Forrest M.D., Ph.D.

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Advances in the Use of Electronic Clinical Data for Prospective Patient Centered Outcomes Research, Ned Calonge, Gurvaneet Randhawa, Emily Beth Devine, John Steiner, Adam Wilcox, and Erin Holve

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Advancing the National Dialogue to Build an Electronic Clinical Data Infrastructure for QI and Research, Erin Holve, Peter Embi, and Bruce Bayley

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Advancing User Experience Research to Facilitate and Enable Patient Centered Research: Current State and Future Directions, Philip Payne

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A Focus Group Exploration of Automated Case‐Finders to Identify High‐Risk Heart Failure Patients within an Urban Safety- Net Hospital, Mark E. Patterson, Derick Miranda, Gregory L. Schuman, Christopher M. Eaton, Andrew J. Smith, and Brad Silver

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A Framework for Usable and Effective Clinical Decision Support: Experience from the iCPR Randomized Clinical Trial, Joseph Kannry, Lauren McCullagh, Andre Kushniruk, Devin Mann, Daniel Edonyabo, and Thomas McGinn

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A Framework to Support the Sharing and Re-Use of Computable Phenotype Definitions Across Health Care Delivery and Clinical Research Applications, Rachel Richesson, Michelle Smerek, and C. Blake Cameron

Afternoon Break, EDM Forum

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A General Framework for Considering Selection Bias in EHR-Based Studies: What Data are Observed and Why?, Sebastien Haneuse and Michael Daniels

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A Harmonized Data Quality Assessment Terminology and Framework for the Secondary Use of Electronic Health Record Data, Michael G. Kahn, Tiffany J. Callahan, Juliana Barnard, Alan E. Bauck, Jeff Brown, Bruce N. Davidson, Hossein Estiri, Carsten Goerg, Erin Holve, Steven G. Johnson, Siaw-Teng Liaw, Marianne Hamilton-Lopez, Daniella Meeker, Toan C. Ong, Patrick Ryan, Ning Shang, Nicole G. Weiskopf, Chunhua Weng, Meredith N. Zozus, and Lisa Schilling

A mobile health infrastructure to support underserved patients with chronic conditions, Henry Fischer

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A Multi-step Maturity Model for the Implementation of Electronic and Computable Diagnostic Clinical Prediction Rules (eCPRs), Derek Corrigan, Ronan McDonnell, Atieh Zarabzadeh, and Tom Fahey

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Analytical Methods for Learning Health Systems, Michael A. Stoto, Erin Holve, Lucy Savitz, Neil S. Fleming, Elisa L. Priest, and Brian S. Mittman

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Analytic Challenges Arising from the STOP CRC Trial: Pragmatic Solutions for Pragmatic Problems, William M. Vollmer, Beverly B. Green, and Gloria D. Coronado

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Analytic Methods, David Madigan and George Hripcsak

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Analytic Methods, Remle Newton-Dame, Karl Mammermeister, Jeremy A. Rassen, and Patrick Ryan

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Analytic Methods, Darren Toh, Beth Devine, and Jay Desai

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Analytic Methods, Darren Toh and Michael Kahn

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Analyzing Patient Care Records Like a Trial to Develop New Knowledge about Clinical Practice, Mike Stoto and Charles Bailey

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An Automated Method for Identifying Individuals with a Lung Nodule Can Be Feasibly Implemented Across Health Systems, Farhood Farjah, Scott Halgrim, Diana S.M. Buist, Michael K. Gould, Steven B. Zeliadt, Elizabeth T. Loggers, and David S. Carrell

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A New Framework and Prototype Solution for Clinical Decision Support and Research in Genomics and Other Data-intensive Fields of Medicine, James Evans, Kirk Wilhelmsen, Jonathan Berg, Charles Schmitt, Ashok Krishnamurthy, Karamarie Fecho, and Stanley Ahalt

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Application of Expert- and Informatics-Based Approaches to Understand the Health-Related Needs of LGBT Populations, Walter Bockting, Nancy Reame, Nicholas Tatonetti, Adriana Arcia, Ragnhildur I. Bjarnadottir, William Brown III, Bobbie Berkowitz, and Suzanne Bakken

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Applications of Electronic Health Information in Public Health: Uses, Opportunities and Barriers, Alan Tomines, Heather Readhead, Adam Readhead, and Steven Teutsch

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Applied Use of Composite Quality Measures for EHR-enabled Practices, Aurora O. Amoah, Sam Amirfar, Sheryl L. Silfen, Jesse Singer, and Jason J. Wang

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Applying Sequential Analytic Methods to Self-Reported Information to Anticipate Care Needs, Elizabeth A. Bayliss, J. David Powers, Jennifer L. Ellis, Jennifer Barrow, Mary Jo Strobel, and Arne Beck

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Appreciating the Nuance of Daily Symptom Variation to Individualize Patient Care, Jeremy Adler, Shehzad A. Saeed, Ian S. Eslick, Lloyd Provost, Peter A. Margolis, and Heather C. Kaplan

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Approaches to Facilitate Institutional Review Board Approval of Multicenter Research Studies, Keith Marsolo

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Approaches to Using Protected Health Information (PHI) for Patient-Centered Outcomes Research (PCOR): Regulatory Requirements, De-identification Strategies, and Policy, Raj Sabharwal, Erin Holve, Alison Rein, and Courtney Segal

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A Pragmatic Framework for Planning Data Management in Effectiveness and Outcomes Research, Elisa L. Priest DrPH; Gabriela Cantu MPH; Ashley Collinsworth MPH; and Andrew Masica MD, MSCI

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A Pragmatic Framework for Single-site and Multisite Data Quality Assessment in Electronic Health Record-based Clinical Research, Michael G. Kahn, Marsha A. Raebel, Jason M. Glanz, Karen Riedlinger, and John F. Steiner

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Assessing the Potential Adoption and Usefulness of Concurrent, Action-Oriented, Electronic Adverse Drug Event Triggers Designed for the Outpatient Setting, Hillary J. Mull, Amy K. Rosen, Stephanie L. Shimada, Peter E. Rivard, Brian Nordberg, Brenna Long, Jennifer M. Hoffman, Molly Leecaster, Lucy A. Savitz, Christopher W. Shanahan, Amy Helwig, and Jonathan R. Nebeker

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Assessing Validity and Quality, and Understanding Context, Michael Kahn, Beth Devine, and Jay Desai

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A Synthesis of Current Surveillance Planning Methods for the Sequential Monitoring of Drug and Vaccine Adverse Effects Using Electronic Health Care Data, Jennifer C. Nelson, Robert Wellman, Onchee Yu, Andrea J. Cook, Judith C. Maro, Rita Ouellet-Hellstrom, Denise Boudreau, James S. Floyd, Susan R. Heckbert, Simone Pinheiro, Marsha Reichman, and Azadeh Shoaibi

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A systematic approach to outcomes assessment of care management programs, Lin Wang, Kara Kuntz-Melcavage, Christopher B. Forrest, Yanyan Lu, Leslie Piet, Kathy Evans, Melissa Sherry, Maria Uriyo, Regina Richardson, Michelle Hawkins, and Donna Neale

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Augmenting Predictive Modeling Tools with Clinical Insights for Care Coordination Program Design and Implementation, Tracy L. Johnson, Daniel Brewer, Raymond Estacio, Tara Vlasimsky, Michael J. Durfee, Kathy R. Thompson, Rachel M. Everhart, Deborath J. Rinehart, and Holly Batal

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Automating Data Abstraction in a Quality Improvement Platform for Surgical and Interventional Procedures, Meliha Yetisgen, Prescott Klassen, and Peter Tarczy-Hornoch

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Availability of Structured and Unstructured Clinical Data for Comparative Effectiveness Research and Quality Improvement: A Multi-Site Assessment., Daniel Capurro MD, PhD; Meliha Yetisgen PhD; Erik van Eaton MD; Robert Black; and Peter Tarczy-Hornoch MD

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A Validation Study of Administrative Claims Data to Measure Ovarian Cancer Recurrence and Secondary Debulking Surgery, Jennifer Livaudais-Toman, Natalia Egorova, Rebeca Franco, Monica Prasad-Hayes, Elizabeth A. Howell, Juan Wisnivesky, and Nina A. Bickell

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Back to the Bedside: Developing a Bedside Aid for Concussion and Brain Injury Decisions in the Emergency Department, Edward R. Melnick, Kevin Lopez, Erik P. Hess, Fuad Abujarad, Cynthia A. Brandt, Richard N. Shiffman, and Lori A. Post

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Beacon Communities’ Public Health Initiatives: A Case Study Analysis, Barbara L. Massoudi MPH, PhD; Laura H. Marcial; Saira Haque; Robert Bailey; Kelley Chester; Shellery Cunningham; Amanda Riley; and Paula Soper

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Benefits of usability testing for the integration of a National substance use screening tool into the Electronic Health Record, Lauren McCullagh, Catherine De Stio, Jeanne Morley MD, Andre Kushniruk PhD, Joseph Conigliaro MD, and Thomas McGinn

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Better Evidence. Better Decisions. Better Health (Part 1): e-Clinical Quality Measures, Daniella Meeker, Michael Sacca, and Helen Burstin

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Better Evidence. Better Decisions. Better Health (Part 2): Clinical Decision Support and User Experience, Thomas McGinn, Emily S. Patterson, Edward R. Melnick, and Derek Corrigan

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Better Evidence. Better Decisions. Better Health (Part 3): Payer Perspectives, Raj Sabharwal and Jennifer Graff

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Bidirectional Data Collaborations in Distributed Research, Kevin Haynes, Nandini Selvam, and Mark J. Cziraky

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Big Data and Big Crowds: Getting Useful Data from Text Fields Using Large Data Sets, Janna L. Friedly, Jeffery G. Jarvik, and Bryan Comstock

Break, EDM Forum

Breakout Discussions: Development of a Collaborative Project Using PRO for CER & PCOR Focused on Asthma and Depression, EDM Forum

Breakout Discussions: PRO Challenge Framework for CER & PCOR, EDM Forum

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Breakout Session: Group 1, Beth Devine, Wilson Pace, and David Chang

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Breakout Session: Group 2, Bernadette Boden-Albala and Paul Dexter

Breakout Summary Discussion, Jason Goldwater, Clete Kushida, Jonathan Nebeker, Michael Oakes, Lucila Ohno-Machado, and Lisa Schilling

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Building a Governance Strategy for CER: The Patient Outcomes Research To Advance Learning (PORTAL) Network Experience, Andrea R. Paolino, Elizabeth A. McGlynn, Tracy Lieu, Andrew F. Nelson, Stephanie Prausnitz, Michael A. Horberg, David E. Arterburn, Michael K. Gould, Reesa L. Laws, and John Steiner

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Building a Learning Health System - Where have We Been, Where are We Going?, Peter Margolis, Suzanne Bakken, Lisa Schilling, and John F. Steiner

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Building and Strengthening Infrastructure for Data Exchange: Lessons from the Beacon Communities, Gretchen Torres, Karen Swietek, Petry S. Ubri, Rachel Singer, Kristina Lowell, and Wilhelmine Miller

Building CER Capacity: Aligning CRN, CMS, and State Resources to Map Cancer Care – Research on the effectiveness of advanced cancer treatments (REACT), Debra P. Ritzwoller and Jane C. Weeks

Building Modular Pediatric Chronic Disease Registries for QI and CE Research, John Hutton

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Building the Electronic Clinical Data Infrastructure to Improve Patient Outcomes: CER Project Profiles, EDM Forum

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Building the Informatics Infrastructure for Comparative Effectiveness Research (CER): A Review of the Grey Literature, Marianne Hamilton Lopez, Rebecca Singer Cohen, and Erin Holve

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Calculating Power by Bootstrap, with an Application to Cluster-randomized Trials, Ken Kleinman and Susan S. Huang

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Can Electronic Health Records Be Used for Population Health Surveillance? Validating Population Health Metrics Against Established Survey Data, Katharine H. McVeigh PhD, MPH; Remle Newton-Dame MPH; Pui Ying Chan MPH; Lorna E. Thorpe PhD; Lauren Schreibstein MS; Kathleen S. Tatem; Claudia Chernov MPH; Elizabeth Lurie-Moroni; and Sharon E. Perlman MPH

Cardiovascular Risk Reduction Learning Community (CRRLC), Karl E. Hammermeister MD

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CDS, UX, and System Redesign – Promising Techniques and Tools to Bridge the Evidence Gap, Thomas McGinn

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CER Infrastructure Investments to Support Evidence Generation in a Learning Health System, Courtney Segal and Erin Holve

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Characterizing an optimal predictive modeling framework for prediction of adverse drug events, Jon Duke, Zuoyi Zhang, and Xiaochun Li

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CHCO_dq.sql, Data Quality Collaborative

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Clinical Data Discovery Tool, Dave Anderson

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Clinical Informatics, Stephan Fihn, Deborah Estrin, and Vivian Gainer

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Clinical Informatics, Kathleen Fuda, Deepthi Rajeev, Ram Gouripeddi, and Beth Devine

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Clinical Informatics, Dean Sittig, Michael Kahn, and Omolola Ogunyemi

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Clinical Informatics, Adam Wilcox and Sachin Kheterpal

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Clinical Informatics, CER, and PCOR: Building Blocks for Meaningful Use of Big Data in Health Care, Mark Frisse, Adam Wilcox, Dean Sittig, Michael Kahn, and Marianne Hamilton Lopez

Clinically enhanced multi-purpose administrative dataset for comparative effectiveness research in the State of Florida, Hamisu M. Salihu

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Closing Panel | Collaborative Approaches to Generating the Evidence We Need in Healthcare, Basit Chaudhry, Brian Bot, Philip R.O. Payne, S. George Djorgovski, and Carl Kesselman

Collaborative National Network Examining Comparative effectiveness Trials (CONNECT), Ben Miller

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Collaborative Patient Engagement in the Design, Conduct, Dissemination and Translation of Patient-Centered Outcomes Research for Back Pain, Danielle C. Lavallee, Janna L. Friedly, Zoya Bauer, Rafael Alfonso-Cristancho, David R. Flum, and Jeffery G. Jarvik

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Collecting and Using Patient-Reported Outcomes (PRO) for Comparative Effectiveness Research (CER) and Patient-Centered Outcomes Research (PCOR): Challenges and Opportunities, Courtney Segal, Erin Holve, and Raj Sabharwal

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Collecting, Integrating, and Disseminating Patient-Reported Outcomes for Research in a Learning Healthcare System, Christopher A. Harle, Gloria Lipori, and Robert W. Hurley

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Collecting Patient Reported Outcomes: Lessons from the California Joint Replacement Registry, Kate E. Chenok, Stephanie Teleki, Nelson F. SooHoo, James Huddleston III, and Kevin J. Bozic

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Collecting Patient Reported Outcomes: Lessons from the California Joint Replacement Registry, Kate E. Chenok, Stephanie Teleki, Nelson F. SooHoo, James Huddleston III, and Kevin J. Bozic

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Collection of Patient-Reported Outcomes in Clinical Practice: Healthcare May Be Ready!, Irene Katzan MD, John Urchek, Cheryl Dunphy RN, Alandra Parchman MHA, Sandra Griffith PhD, Charles Bae MD, Lara Jehi MD, and Micheal Speck

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Commentary: Clinical Informatics, Mark E. Frisse

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Commentary: Electronic Health Records for Comparative Effectiveness Research, Russell E. Glasgow

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Commentary : Protecting Human Subjects and Their Data in Multi-Site Research, Harold S. Luft

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Community Health Needs Assessments: Filling Data Gaps for Population Health Research and Management, Philip Alberti

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Comparative Effectiveness Research (CER) and Clinical Informatics: An Annotated Bibliography, Marianne Hamilton Lopez, Sonia Nagda, Erin Holve, and Neil Sarkar